Healthcare Payments Data (HPD): Fee-For-Service Drug Costs

This data includes the top 25 list for costliest prescribed drugs, most frequently prescribed drugs and the prescribed drugs with the highest monthly median out-of-pocket cost for members. Each of these top 25 lists are broken out by payer type (i.e., All Payers, All Payers W/O Medi-Cal, Commercial, Medicare or Medi-Cal) and drug category (i.e., All, Brand, Generic, Biosimilar or Biologic). The includes National Drug Code (NDC), Year, Top 25 Ranking, National Drug Code, Drug Name, number of prescriptions, number of individuals, total costs, average cost per unit, average dispensed units per fill, drug unit of measure, monthly median out-of-pocket cost, 25th percentile for monthly out-of-pocket cost, 75th percentile for monthly out-of-pocket cost, and percent of monthly out-of-pocket cost with zero dollar amounts for each NDC in each top 25 list.

Data files

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Healthcare Payments Data (HPD): Fee-For-Service Drug Costs Data Dictionary

The data set includes the top 25 list for costliest prescribed drugs, most frequently prescribed drugs and the prescribed drugs with the highest monthly median out-of-pocket costs. Each of these top 25 lists are given for commercial plans and are broken out by brand or generic category (i.e., Brand or Generic, Brand, and Generic). The includes National Drug Code (NDC), Drug Name, number of prescriptions, number of individuals, total costs, cost per prescription and monthly median out-of-pocket costs for each NDC in each top 25 list.


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CSV
11/20/25

All resource data


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ZIP
11/20/25

Supporting files

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Healthcare Payments Data (HPD): Fee-For-Service Drug Costs Data (November 2025)

This data includes the top 25 list for costliest prescribed drugs, most frequently prescribed drugs and the prescribed drugs with the highest monthly median out-of-pocket cost for members. Each of these top 25 lists are broken out by payer type (i.e., All Payers, All Payers W/O Medi-Cal, Commercial, Medicare or Medi-Cal) and drug category (i.e., All, Brand, Generic, Biosimilar or Biologic). The includes National Drug Code (NDC), Year, Top 25 Ranking, National Drug Code, Drug Name, number of prescriptions, number of individuals, total costs, average cost per unit, average dispensed units per fill, drug unit of measure, monthly median out-of-pocket cost, 25th percentile for monthly out-of-pocket cost, 75th percentile for monthly out-of-pocket cost, and percent of monthly out-of-pocket cost with zero dollar amounts for each NDC in each top 25 list.


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XLSX
11/20/25

Healthcare Payments Data (HPD) Fee-For-Service Drug Costs Technical Note (November 2025)


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PDF
11/20/25

Healthcare Payments Data (HPD) Fee-For-Service Drug Costs by Commercial Plans Technical Note (Original Launch Version)


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PDF
09/22/24